Brain has a complex phenomenon that can change the process of life. This capacity of the brain to change is called brain plasticity. There are a number of factors that influence brain and lead to its changes. In their article “Brain Plasticity and Behavior”, Kolb, Gibb, and Robinson explain the nature of brain plasticity, consider the possible factors that lead to brain change, and arrive to the conclusion about the importance of studying brain plasticity. Researchers estimate that capacity to change is one of the key characteristics of nervous system including brain. As a result of change in nervous system, brain is also changed, and so is behavior. Brain plasticity may lead to change in behavior both in normal and abnormal way. The nature of brain plasticity lies in the fact that behavior changes in response to certain alterations that occur in brain circuits. Those alterations are usually measured with the technique suggested by Camillo Golgi and allowing to estimate differences in synapses located in certain regions of brain. As a result of studying brain change, it has been found out that experience is one of the leading factors that affect brain plasticity. Research shows that this experience can be both prenatal and postnatal. In addition, there is a whole range of other factors that have a significant impact on the neuronal structure and behavior. Among those factors are psychoactive drugs, gonadal hormones, and anti-inflammatory agents; growth, dietary, and genetic factors; certain diseases; stress; brain injury and leading disease (Kolb, Gibb, & Robinson ). When scientists conducted research of various age groups affected by the same factors, they discovered important qualitative differences in neuronal structure change between young and adult sample. Certain prenatal and postnatal experience had a clear long-term impact on neuronal structure as well. It was also noticed that different factors influence neuronal structure in different ways and to a different extent.